Sport-related concussion (SRC) is a complex injury, and SRCs are notably prevalent among National Collegiate Athletic Association (NCAA) athletes. We analysed SRCs and associated exposure data collected within the NCAA Injury Surveillance Program during 2014-2019. A total of 1,709 SRCs were reported with complete symptom profiles during the study period (Women`s sports n = 499; Men`s sports n = 1,210). Event type and academic class year most commonly predicted specific symptom presentations among athletes in men`s sports, while symptom presentation among athletes in women`s sports was most commonly predicted by class year and sport classification. We observed 78 and 69 significant pairwise symptom dependencies in men`s and women`s sports athletes, respectively; odds of longer symptom resolution time were higher with greater counts of symptoms with strongest cross-domain associations. Our findings highlight several contextual predictors of specific symptom presentations and identify parsimonious symptom subsets that may indicate protracted recovery among men`s and women`s sports athletes.
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